I'd appreciate any feedback regarding my upcoming geared 36er build

Definitely most of the frames (including the mad4one) won’t fit without modification. A the M-series hubs were developed with Kris Holm, KH-Frames were always the only ones fitting on the hub out of the box. You can read more on this topic here:

Most frames (except KH) do not fit this measurements:


The generation M5 hubs may have some additional requirements but i guess, these measurement shown in the picture will remain the same.
What it takes to modify a QX-Frame is decribed in the linked thread. For the mad4one frame, there’s @muni_ben who comes to my mind first who has done the modification.