Does anyone have a photo of a unicycle with a disc hub from the front view? I’m having a hard time visualizing how the wheel would be centered in the frame…
Apologies for the terrible and quick paint job.
If green is your wheel, and red is the disc brake, black being the frame:
A photo may not capture this well because of the thickness of the tire. Anyway, on an inside mounted disc hub, the spokes must be different lengths on different sides of the wheel. They will have different tensions as well. This is known as “dishing” a wheel.
On an outside mounted disc brake, you can have a symmetrical wheel obviously so it doesn’t matter. Either way, you can center the wheel. Note that on a dished wheel, there is less triangulation, which could, in theory make it a slightly less rigid wheel, which lends it to failure quicker, but with modern materials, this really isn’t too big of an issue.
Thanks so much! That is exactly what I was wanting to know. 
Just look at any bike with disc brakes.
Disc hub
Juggleaddict posted a good representation, check my page and go to albums, though home made I’ve been riding inside the frame disc hub for over 15 years with none of the problems that have been speculated about on the forums