It’s not ideal, but there are ways to make it work.
I think that frame is made for 40mm bearings, and ISIS hubs have 42mm bearings. It has pressed bearing holders, and some people have had success with putting 42mm bearings in them without much trouble, but I think you would be better to have bearings that fit your bearing holders.
You could use the new bearings with adaptors to fit an ISIS hub on that frame, but that will add $26 to the price of the ISIS hub. Once you start spending that kind of money to retrofit a new hub to an old frame it starts to make sense to just get a new frame.